Sodium metatungstate

CAS No. 12141-67-2

Sodium metatungstate( Sodium polyoxotungstate | POM-1 )

Catalog No. M23382 CAS No. 12141-67-2

Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 39 In Stock
50MG 56 In Stock
100MG 81 In Stock
500MG 203 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Sodium metatungstate
  • Note
    Research use only, not for human use.
  • Brief Description
    Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
  • Description
    Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Multiple myeloma (MM) mice developed by 3 weeks of injection of 5t33MM cells Dosage:5 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Had significantly lower spleen weights, fewer tumor cells in the spleen as well as significantly lower monoclonal immunoglobulin component level in circulation.
  • Synonyms
    Sodium polyoxotungstate | POM-1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    12141-67-2
  • Formula Weight
    2869.03
  • Molecular Formula
    H2Na6O40W12
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: 48 mg/mL (16.07 mM; Need ultrasonic); DMSO: 48 mg/mL (16.07 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Müller CE, et al. Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7.
molnova catalog
related products
  • GDC-0623

    GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.

  • Acetovanillone

    Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).

  • Phenazoline

    Argireline a synthetic peptide which is patterned from the N-terminal end of the protein SNAP-25 can both reduce the degree of existing facial wrinkles and demonstrate effectively against their development.